Do things NOW, to your existing motor, which will transfer to a more powerful motor down the road.
Several years ago, I stumbled upon a great deal on a 455. It had "66" casting heads and beveled-edge pistons, resulting in just 7.8:1 compression.
I designed my own low-lift camshaft (0.443/0.435"). A Q-jet on a Performer intake, stock HEI, and the factory log manifolds. On a DynoJet chassis dyno, it put 225hp to the wheels - better than I expected.
Next I installed a set of headers. I used a set of tri-Y headers, which I am afraid are no longer available. But I would expect similar results with a set of quality 4 into 1 headers, like Doug's. I gained 45rwhp, and extended the power band much further.
Next I replaced the entire exhaust system with 3" pipes, 3" Borla ProXS mufflers, and an H-pipe. Now, all the "experts" SWEAR that was "too much" exhaust for such a mild motor. Yet, I gained over 15 more rwhp.